Corpora amylacea in the neocortex in patients with temporal lobe epilepsy and focal cortical dysplasia

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Corpora amylacea in the neocortex in patients with temporal lobe epilepsy and focal cortical dysplasia.

INTRODUCTION Corpora amylacea (CoA) are present in about 60% of atrophic hippocampi resected from patients with drug resistant temporal lobe epilepsy (DRTLE). They have also been described in the lateral temporal neocortex, although less frequently. OBJECTIVE The objective is to measure the presence, distribution and density of CoA in the lateral temporal lobes of patients with DRTLE and foca...

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Corpora amylacea in temporal lobe epilepsy associated with hippocampal sclerosis.

UNLABELLED Hippocampal sclerosis (HS) is the commonest pathology in epileptic patients undergoing temporal lobe epilepsy surgery. Beside, there are an increased density of corpora amylacea (CA) founded in 6 to 63% of those cases. OBJECTIVE verify the presence of CA and the clinical correlates of their occurrence in a consecutive series of patients undergoing temporal surgery with diagnosis of...

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Emotion Processing in Patients with Early- and Late-Onset Temporal Lobe Epilepsy

Objective: Temporal Lobe Epilepsy (TLE) can contribute to various emotional symptoms by damaging the temporal lobe. This study aimed at investigating emotion processing in patients with early- and late-onset TLE compared to a healthy group. Methods: In this causal-comparative study, 60 patients with diagnosed TLE were compared to 60 healthy controls to identify emotion processing styles. The d...

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Familial temporal lobe epilepsy due to focal cortical dysplasia type IIIa

PURPOSE Focal cortical dysplasia (FCD) represents a common cause of refractory epilepsy. It is considered a sporadic disorder, but its occasional familial occurrence suggests the involvement of genetic mechanisms. METHODS Siblings with intractable epilepsy were referred for epilepsy surgery evaluation. Both patients were examined using video-EEG monitoring, MRI examination and PET imaging. Th...

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Echinoderm microtubule-associated protein -like protein 5 in anterior temporal neocortex of patients with intractable epilepsy

Objective(s):EMAP-like Protein 5 (EML5) is a new echinoderm microtubule-associated protein that is expressed in the central nervous system. The aim of this study was to investigate the expression profile of EML5 in the anterior temporal neocortex of patients presenting with intractable epilepsy (IE). Materials and Methods:Western blot assays were performed to determine EML5 expression in 36 su...

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ژورنال

عنوان ژورنال: Neurología (English Edition)

سال: 2015

ISSN: 2173-5808

DOI: 10.1016/j.nrleng.2013.06.014